Modifying genetic diseases: Promises to be realized?
نویسندگان
چکیده
منابع مشابه
Cyclic nucleotide phosphodiesterase 5 and sildenafil: promises realized.
PDEs belong to a large superfamily [11 different gene families (PDEs 1–11)] of structurally related, functionally distinct, and highly regulated enzymes (Francis et al., 2001). Most PDE families comprise more than one gene ( 20 PDE genes), which generate multiple protein products ( 50 PDE proteins) via alternative mRNA splicing or use of different promoters/transcription initiation sites. Most ...
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ژورنال
عنوان ژورنال: Cleveland Clinic Journal of Medicine
سال: 2020
ISSN: 0891-1150,1939-2869
DOI: 10.3949/ccjm.87b.01020